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- Alzheimer’s Caregivers at Risk for Depression
- Inflammatory Bowel Disease May Put You at Risk for Alzheimer’s
- Why More Women Than Men Get Alzheimer’s Disease
- Stress May Increase Your Alzheimer’s Risk; Take Steps to Reduce It
- Sleeping Pills May Increase Your Dementia Risk
- Poor Vision May Increase Your Risk of Dementia
- Stay Social! Being Alone Can Increase Your Alzheimer’s Risk
- High or Low Blood Pressure May Raise the Risk of Dementia
- How Alcohol Might Affect Your Dementia Risk
- The Hidden Costs of Alzheimer’s Disease
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- Being Overweight May Be Bad for Your Brain
- Heart Risks Tied to Increased Dementia Risks
- ‘A4’ Study Links Beta-Amyloid to Early Alzheimer’s
- Stay Social! Being Alone Can Increase Your Alzheimer’s Risk
- Depression Increases the Risk of Alzheimer’s Disease
- Poor Sleep Tied to Rise in Alzheimer’s Protein in Blood
- Air Pollution Tied to Alzheimer’s Brain Changes
- The Tau of Alzheimer’s
- Anemia Tied to Alzheimer’s Risk
- ‘Squeezed’ Blood Vessels in the Brain May Contribute to Alzheimer’s Onset
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- A Reminder to Keep Taking Your Blood Pressure Medications
- Take Your Blood Pressure Meds. It May Reduce Your Alzheimer’s Risk.
- Drug Company to Pursue Approval of Aducanumab, New Drug for Alzheimer’s
- Drugs May Not Be the Best Choice for Easing the Agitation of Alzheimer’s
- Alzheimer’s Drug May Lead to Life-Threatening Muscle Disease
- Opioid Painkillers Increase Pneumonia Risk in People With Alzheimer’s Disease
- Drug Companies Halt Trials of Aducanumab for Alzheimer’s Disease
- Diabetes Treatments May Help Ward Off Alzheimer’s Disease
- Can Mushrooms Help Your Memory?
- Buyer Beware: Dietary Supplement’s Won’t Cure Alzheimer’s Disease
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- Brush, Floss and Visit the Dentist to Lower Your Risk of Alzheimer’s Disease
- How Music and Film Can Teach People About Alzheimer’s Disease
- Deep Sleep May Help Protect the Brain Against Alzheimer’s Onset
- Flu and Pneumonia Vaccines May Help Protect Against Alzheimer’s Disease
- Fish as Brain Food, Combating the Effects of Pollution
- 5 Ways to Lower Your Alzheimer’s Risk
- Modest Amounts of Fruits and Vegetables May Lower Your Alzheimer’s Risk
- Processed Meat and Starchy Foods, Particularly in Combination, May Raise Dementia Risk
- Stay Social! Being Alone Can Increase Your Alzheimer’s Risk
- A Daily Aspirin May Have Limited Brain Benefits
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- A Blood Test for Alzheimer’s? It May Be Coming
- The Ups and Downs of New Treatments for Alzheimer’s Disease
- A Rare Genetic Mutation May Protect Against Alzheimer’s
- Income Drops in Young Adulthood May Impair Brain Health
- Blood Test for Alzheimer’s Grows Closer
- Are We Getting Closer to an Alzheimer’s Vaccine?
- Why More Women Than Men Have Alzheimer’s Disease
- Scientists get a ‘total surprise’ and a promising new clue for how to cure Alzheimer’s
- Some 44 Million People Have Alzheimer’s Worldwide
- Nearly 14 Million Americans Will Have Alzheimer’s Disease by 2060
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- Fisher Center in Top 1% of Charities Again
- Important Message from Us to You during COVID-19
- Lucretia V. Holden promoted to Executive Director at the Fisher Center
- The Fisher Center for Alzheimer’s Research Foundation Earns Coveted 4-Star Rating from Charity Navigator for the 8th Consecutive Year
- Fisher Center For Alzheimer’s Research Foundation Wins Fall 2018 Digital Health Awards®
- Fisher Center for Alzheimer’s Research Foundation Earns Gold Seal of Transparency from GuideStar
- The Fisher Center for Alzheimer’s Research Foundation Earns Coveted 4-Star Rating from Charity Navigator for the 7th Consecutive Year
- Hear Kent Karosen, President and CEO of the Fisher Center for Alzheimer’s Research Foundation, describe his new book and the power of art therapy
- Fisher Center Scientists link a Mutation That Protects Against the Development of Alzheimer’s Disease
- Newly Inducted Into the Basketball Hall of Fame, Shaquille O’Neal, Joins the Fisher Center for Alzheimer’s Research Foundation to Raise Funds for Groundbreaking Research in the Quest for a Cure
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Useful Definitions
July 31, 2010
Here are definitions for some common terms used in clinical trials.
Placebo:
A placebo (sometimes called a “sugar pill”) is an inactive pill, liquid, or powder that has no treatment value. In clinical trials, experimental treatments are often compared with placebos to assess the treatment’s effectiveness. In some studies, the participants in the control group will receive a placebo instead of an active drug or treatment.
Control group:
A control is the standard by which experimental observations are evaluated. In many clinical trials, one group of patients will be given an experimental drug or treatment, while the control group is given either a standard treatment for the illness or a placebo.
Blinded study:
A blinded or masked study is one in which participants do not know whether they are in the experimental or control group in a research study. Those in the experimental group get the medications or treatments being tested, while those in the control group get a standard treatment or no treatment.
Double-blinded study:
A double-blind or double-masked study is one in which neither the participants nor the study staff know which participants are receiving the experimental treatment and which ones are getting either a standard treatment or a placebo. These studies are performed so neither the patients’ nor the doctors’ expectations about the experimental drug can influence the outcome.
Side effects:
Side effects are any undesired actions or effects of drug or treatment. Negative or adverse effects may include headache, nausea, hair loss, skin irritation or other physical problems. Experimental treatments must be evaluated for both immediate and long-term side effects.
For more useful definitions related to clinical trials, visit ClinicalTrials.gov Glossary.
