The niece of late Zachary and Elizabeth Fisher, Dr. Kenowsky conducts Alzheimer’s research at the Fisher Alzheimer’s Disease and Education program at NYU school of Medicine with a goal to change the standard of care for AD patients by determining the added value of an individualized care management program for Alzheimer’s patients receiving memantine. Subjects with moderate to severe AD are eligible. All patients will be randomly assigned to one of two groups. Patients in both groups will receive memantine and follow up evaluations at no cost to them. Additionally, one group will receive compensation and the other group will receive an individualized management program consisting of home visits to get the patient exercising, doing enjoyable activities, and cognitive stimulation, as well as support and training for caregivers.