What particular part of the brain does Alzheimer’s effect?

Alzheimer’s is first detected in the hippocampus, an area of the brain responsible for recent learning and more complex thoughts.  From there the disease spreads out to the other sections of the brain as the disease continues to progress.  Eventually, Alzheimer’s affects all aspects of everyday living and, in the end-stages, even the immune system is compromised. The person becomes susceptible to recurrent infections which quite often lead to the immediate cause of death.