Tag Archives: beta-amyloid

Fisher Scientists Discover Protein that Fuels Alzheimer’s Disease, Promising New Treatments Expected

Researchers at the Fisher Center for Alzheimer’s Research laboratory published “Gamma-secretase Activating Protein is a Therapeutic Target for Alzheimer’s Disease” in Nature online on September 1, 2010.  Drs. Gen He (lead author) and Paul Greengard have discovered a protein that stimulates the … Continue reading

Plain Talk About Alzheimer’s Research

At the Fisher Center for Alzheimer’s Research Foundation, we are funding innovative Alzheimer’s research that is beginning to make serious headway. I wanted to talk to you not as a scientist, but as a regular guy originally from the Midwest, … Continue reading

Curing Early-Onset Alzheimer’s

While being diagnosed with Alzheimer’s can be overwhelming at any age, it is particularly devastating when the disease strikes early in one’s life. Early-onset Alzheimer’s can present itself in people as young as 30 and it is strongly inherited, affecting … Continue reading

Recruiting Stress Proteins to clean up tangles in the brain

The brains of people with Alzheimer’s contain large numbers of plaques and tangles. Plaques are formed from beta-amyloid. Tangles are made of a protein called tau. Like beta-amyloid, tangles can also damage the brain and thus contribute to the devastating … Continue reading

Reversing Nerve Cell Damage

The devastating loss of memory that is the hallmark of Alzheimer’s disease is caused by the death of nerve cells “strangled” by beta amyloid. In what would have seemed like science fiction a decade ago, the Fisher Center Foundation’s scientists … Continue reading

Beating Back Beta Amyloid

The Fisher Center for Alzheimer’s Research Foundation funds scientists who continue to be at the forefront of research into the understanding of beta amyloid, a protein that is at the root of Alzheimer’s disease. Beta amyloid forms dense protein deposits … Continue reading

Casein Kinase 1

Proceedings of the National Academy of Sciences February 26, 2007 Full PDF: Click Here New therapeutic target for Alzheimer’s could lead to drugs without side effects Researchers from the Fisher Center for Alzheimer’s Research Center at The Rockefeller University have … Continue reading

Our Alzheimer’s Research

Our team of internationally renowned scientists, under the direction of Nobel laureate Dr. Paul Greengard, has been at the forefront of seminal research that has provided a conceptual framework for modern day investigations into Alzheimer’s disease. Our groundbreaking research is the … Continue reading

Certain Foods May Protect Against Alzheimer’s Disease

July 31, 2010 Researchers in New York studied the diets of older men and women and found that certain foods may be especially effective in helping to protect against Alzheimer’s. The findings appeared online in the Archives of Neurology, a … Continue reading

Genetic Risk Factors

Scientists who study the genetics of Alzheimer’s distinguish between “familial Alzheimer’s disease,” which runs in families, and “sporadic Alzheimer’s disease”, where no obvious inheritance pattern is seen. True familial Alzheimer’s disease accounts for less than 5% of Alzheimer’s cases. Sporadic … Continue reading