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Home > About Alzheimer's and Dementia > Understanding Alzheimer's Disease > Alzheimer's Symptoms

Alzheimer's Stages & Symptoms

Symptoms

 Alzheimer's Symptoms
 Alzheimer's Risk Factors
 Mild Cognitive Impairment
 Health And Symptoms
 Alzheimer's Progression
 Clinical Stages of Alzheimer's Disease
 Diagnosing Alzheimer's

 


Alzheimer's Symptoms

It's not uncommon to occasionally forget dates or lose items, and these events may become more common as we age. But while occasional memory slippage may be a normal consequence of getting older, Alzheimer's disease is not. If memory problems interfere with one's day-to-day activities, it may be time to seek a doctor's help.

It's important to understand the early signs of Alzheimer's and to seek a medical diagnosis if several symptoms are noticed. Often, it is a family member or close associate who first notices a change in the behavior or mood of a loved one; these people are instrumental in helping the person to get medical care.

Click here for a list of top 10 Alzheimer's Symptoms, a self-assessment tool developed by the Alzheimer's Association.

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Alzheimer's Disease Risk Factors

Scientists have made significant progress in understanding the possible causes of Alzheimer's disease, but many questions remain. It is likely that many factors, both inherited and environmental, interact in complex, poorly understood ways to cause the disease. (Also see Risk Factors below.)

In addition to investigating what might trigger Alzheimer's in some people, scientists have identified a number of brain changes that are associated with Alzheimer's. These include the characteristic plaques and tangles around and inside nerve cells that were first described by the German physician Alois Alzheimer in 1906. (More detail below in What happens to the brain in Alzheimer's disease?)

Click here to learn what scientific research is revealing about the possible causes of Alzheimer's disease.

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What Is Mild Cognitive Impairment?

Mild Cognitive Impairment, or MCI, is increasingly being used to describe a syndrome of memory impairment that does NOT significantly impact daily activities and is not accompanied by declines in overall cognitive function. Researchers have found that 6 percent to 25 percent of people with MCI progress to Alzheimer's, which has raised questions about whether MCI might represent some kind of "transitional stage" between normal aging and dementia. In fact, many experts believe that MCI, as well as age-related memory loss, may always be an early form of Alzheimer's, and progression to symptomatic Alzheimer's disease may be only a matter of time. In some people, the progression may be very slow, so the person may die of other causes before displaying the full spectrum of Alzheimer's symptoms. MCI is now recognized as a clinical condition that requires ongoing assessment and possibly treatment to delay its progression.

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Health And Alzheimer's Symptoms

Memory loss and other problems with cognition or mood could have causes other than Alzheimer's disease. That's why medical evaluation is so important. Other possible causes include side effects of medications; certain illnesses such as small strokes or cerebrovascular disease; thyroid gland problems; depression; fatigue; grief; vision or hearing loss; alcohol use; and potentially even chronic stress. Some of these are treatable or even reversible.

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Alzheimer's Symptoms Progression

Alzheimer's disease is progressive, which means that symptoms worsen over time. How fast the disease progresses, and what pattern symptoms might follow, is variable by individual.

Researchers and doctors use a number of scales to measure the progression of symptoms over time, which may define as many as seven distinct stages of the disease. For general purposes, three broad phases are typically recognized: mild, moderate and severe. The symptoms commonly seen in each stage are summarized below, but it's important to realize that there may be some overlap among the stages, and that people may not experience all of these symptoms.

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Clinical Stages of Alzheimer's Disease

New York University's Dr. Barry Reisberg outlines the seven major clinical stages of Alzheimer's disease.  Dr. Reisberg is the Clinical Director of New York University's Aging and Dementia Research Center. As the principal investigator of studies conducted by the National Institutes of Health, Dr. Reisberg's work has been pivotal in the development of two of the three current pharmaceutical treatment modalities for Alzheimer's. His rating scales and descriptions of the nature and course of Alzheimer's are widely used throughout the world.

Click Here For Clinical Stages of Alzheimer's Disease

 

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Diagnosing Alzheimer's Disease

The only way to know for sure is to obtain a medical diagnosis from a well-trained medical professional, who will determine if symptoms might be due to other causes. If Alzheimer's is the diagnosis, treatment should be started as soon as possible so that the person with the disease can be as involved as possible in treatment decisions and planning for the future.

Facing the possibility of an Alzheimer's diagnosis in yourself or a loved one can be traumatic. While it may be a difficult step, taking action to see a doctor right away for a diagnostic evaluation may actually help resolve anxiety. If Alzheimer's is found to be probable, your doctor can help you understand what to expect, how best to maximize quality of life, and how to find the support and resources that you will need. You may also find it helpful to consult a counselor, spiritual advisor (such as a minister or rabbi), or psychiatrist - someone who can help you and your family cope with the emotional and psychological burden of Alzheimer's.

Learn more at:www.nlm.nih.gov/medlineplus/memory.html

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© 2008 The Fisher Center for Alzheimer's Research Foundation, a 501c3 not for profit, Tax ID # 13-3859563.

This project was supported, in part, by a grant, number 90AZ2791, from the Administration on Aging, Department of Health and Human Services, Washington, D.C. 20201. Grantees undertaking projects under government sponsorship are encouraged to express freely their findings and conclusions. Points of view or opinions do not, therefore, necessarily represent official Administration on Aging policy.