Dr. Karima Bettayeb, Research Associate at the Fisher Center for Alzheimer's Research at The Rockefeller University
Dr. Bettayeb’s research focuses on the identification of novel cellular mechanisms involved in the pathophysiology of Alzheimer’s disease. Specifically, Dr. Bettayeb investigates how specific proteins move about within brain cells (a process known as “trafficking”) and how the regulation of these movements impact on the risk of Alzheimer’s disease. Her research has resulted in the discovery that reducing the levels of a specific protein involved in trafficking blocks the production of beta-amyloid and reduces the number of amyloid plaques in the brains of mice bred with Alzheimer’s models. Dr. Bettayeb’s work is expected to result in the discovery of novel targets within brain cells that can be targeted by drugs to combat Alzheimer’s disease.